Crossover Interference on NOR-bearing Chromosomes in Arabidopsis
نویسندگان
چکیده
Sandy Lam*, Sarah R. Horn*, Sarah J. Radford, Elizabeth A. Housworth, Franklin W. Stahl and Gregory P. Copenhaver* * Department of Biology and The Carolina Center for Genome Sciences, The University of North Carolina at Chapel Hill, Chapel Hill, NC 27599, Curriculum in Genetics and Molecular Biology, The University of North Carolina at Chapel Hill, Chapel Hill, NC 27599, Departments of Mathematics and Biology, Indiana University, Bloomington, IN 47405, Institute of Molecular Biology, University of Oregon, Eugene, OR 97403-1229
منابع مشابه
Crossover interference on nucleolus organizing region-bearing chromosomes in Arabidopsis.
In most eukaryotes, crossovers are not independently distributed along the length of a chromosome. Instead, they appear to avoid close proximity to one another--a phenomenon known as crossover interference. Previously, for three of the five Arabidopsis chromosomes, we measured the strength of interference and suggested a model wherein some crossovers experience interference while others do not....
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In most organisms that have been studied, crossovers formed during meiosis exhibit interference: nearby crossovers are rare. Here we provide an in-depth study of crossover interference in Arabidopsis thaliana, examining crossovers genome-wide in >1500 backcrosses for both male and female meiosis. This unique data set allows us to take a two-pathway modeling approach based on superposing a fract...
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During meiosis, homologous chromosomes (homologs) perform reciprocal exchanges (crossovers) at a high frequency. Crossovers display interference, i.e. their spacing is more even than would be expected if they were placed randomly along the chromosomes. Concomitantly with crossover formation, synaptonemal complexes (SCs) appear between homologs: each chromosome forms an axial structure, the axia...
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